May 2026 NICE Guideline Update

May 10

Guideline Update · May 2026

Six NICE refreshes. Already patched.

Between February and April 2026, NICE re-reviewed six guidelines covering some of the most heavily examined topics on PLAB 1 and the UKMLA AKT — type 2 diabetes, suspected cancer referral, and menopause. These aren’t wording tweaks. They move the first-line drug, the referral threshold, and the escalation step.

Published 10 May 2026 · 5 min read · Reviewed by the MedRevisions team

Our medical team has already updated every affected MCQ explanation, expert note and personalised revision note across the platform — in lockstep with each NICE update going live. You can keep revising as normal.

NG28

Type 2 diabetes management — first-line logic reworked for adults with and without comorbidities; insulin recommendations revised after product withdrawals. Last reviewed 18 Feb 2026

QS209

T2D quality standard — SGLT-2 inhibitor statement extended to all adults with T2D, not just cardiovascular or heart-failure patients. The single highest-yield diabetes change for 2026. Last reviewed 18 Feb 2026

NG12

Suspected cancer referral — new age-banded CA125 thresholds for ovarian cancer, updated endometrial recommendations, plus a new non-site-specific weight-loss rec. Last reviewed 15 Apr 2026

CG122

Ovarian cancer — the primary-care detection section was removed entirely. NG12 is now the only source of truth for the GP’s decision. Last reviewed 15 Apr 2026

QS18

Ovarian cancer quality standard — updated alongside NG12, including the placeholder statement prioritised in 2025. Last reviewed 15 Apr 2026

NG23

Menopause — amended escalation advice for vaginal bleeding on systemic HRT. Small wording change, disproportionate mark impact. Last reviewed 15 Apr 2026

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For the full exam-specific breakdown, see the deeper articles on our dedicated platforms: PLAB 1 Guideline Refresh — May 2026 or UKMLA AKT Guideline Refresh — May 2026.

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Last reviewed 10 May 2026 by the MedRevisions team. Source hierarchy: NICE · BNF · CKS · SIGN · GMC. Spot something off? Email contact@medrevisions.com.

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